CC Kitanovski (ckitanovski@shield-legal.com)
2025-08-13 18:37:02

Hi @James Scott, wanted to say a quick hello. Here is the link to the JPML website which posts all current/pending MDLs as well as those that have been terminated. I'm not sure which report would be most useful to you, but they provide the same information in several different list formats. If there is a way to include which drugs already have a pending MDL (or not), that would be extremely useful. Happy to help however I can, feel free to reach out if there's anything I can do.

James Scott (jamesscott@shield-legal.com)
2025-08-13 18:37:34

Thank you so much! Yes we are going to need to catch up

CC Kitanovski (ckitanovski@shield-legal.com)
2025-08-13 18:38:31

No problem, happy to hop on a call anytime 🙂

James Scott (jamesscott@shield-legal.com)
2025-08-13 18:39:18

Yes let’s talk tomorrow since to will be using the app to get some guidelines on how you would use it and feature enhancements

James Scott (jamesscott@shield-legal.com)
2025-08-13 18:39:29

And introductions!

CC Kitanovski (ckitanovski@shield-legal.com)
2025-08-13 18:40:52

I'll be in office from 7:45am_4:30pm-ish PST and I have no other calls scheduled for tomorrow, so I'm free when you are

CC Kitanovski (ckitanovski@shield-legal.com)
2025-08-13 18:41:19

Yeah, the lunch introductions were rough 😂

James Scott (jamesscott@shield-legal.com)
2025-08-13 18:41:45

Very rough couldn’t hear anything 😂 😂 😂

CC Kitanovski (ckitanovski@shield-legal.com)
2025-08-13 18:42:30

All I heard was sandwiches being chewed around me.

CC Kitanovski (ckitanovski@shield-legal.com)
2025-08-13 18:44:58

I'm packing up to head home. My work email is ckitanovski@shield-legal.com just shoot me a meeting invite for whatever time is good for you tomorrow. See you then!

James Scott (jamesscott@shield-legal.com)
2025-08-13 18:47:08

Sounds good it’s late for me here I will send it in the morning !

CC Kitanovski (ckitanovski@shield-legal.com)
2025-08-13 20:11:45

For sure, sounds good!

CC Kitanovski (ckitanovski@shield-legal.com)
2025-08-24 10:00:04

Morning @James Scott! Do you have some time this week to connect and discuss medilens validation?

James Scott (jamesscott@shield-legal.com)
2025-08-24 16:15:05

yes!! let me get something on our schedule so we can connect!

James Scott (jamesscott@shield-legal.com)
2025-08-24 16:15:09

@CC Kitanovski

CC Kitanovski (ckitanovski@shield-legal.com)
2025-08-24 19:38:51

@James Scott Awesome! Here's my week so far (in PST), let me know when you have time and we'll get it scheduled

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James Scott (jamesscott@shield-legal.com)
2025-08-25 10:27:56

you are pst correct so ur day starts at or would be 11 am my time what timedo u sign on

CC Kitanovski (ckitanovski@shield-legal.com)
2025-08-25 10:38:49

Now-ish on Mondays lol.

CC Kitanovski (ckitanovski@shield-legal.com)
2025-08-25 11:03:58

Mon & Tues, I'm on by 8:45AM the latest. Gotta get the three tiny humans to school. On Weds, Thurs, & Fri, I am on by 7:30AM PST the latest.

James Scott (jamesscott@shield-legal.com)
2025-08-25 11:34:40

ok i can message u tomoror wmorning and we can have the meeting!

CC Kitanovski (ckitanovski@shield-legal.com)
2025-08-25 11:41:19

Okay sounds good, I'll keep an eye out for the message.

CC Kitanovski (ckitanovski@shield-legal.com)
2025-08-29 12:11:24

@James Scott can you send me a screenshot of the medilens screen when you're looking at dupixent so I can explain to Cam that the lymphoma he wants happens to fall under the something-something-melanoma category which happens to be, in plain-english-words... "skin cancer." I can't remember what that column was named in your system

James Scott (jamesscott@shield-legal.com)
2025-08-29 12:13:04

Neoplasms !

James Scott (jamesscott@shield-legal.com)
2025-08-29 12:13:19

And I was typing up a message myself lol you can handle it let me look

James Scott (jamesscott@shield-legal.com)
2025-08-29 12:13:52

Was the category that it falls under for a icd 10 code perspective

CC Kitanovski (ckitanovski@shield-legal.com)
2025-08-29 12:14:26

maybe i misspoke. what category was it that you pointed to that the lymphoma would fall under?

James Scott (jamesscott@shield-legal.com)
2025-08-29 12:14:43

Neoplasms

CC Kitanovski (ckitanovski@shield-legal.com)
2025-08-29 12:15:05

maybe my adderall hasnt kicked in yet then... wasnt it longer?

James Scott (jamesscott@shield-legal.com)
2025-08-29 12:15:15

Is the medical diagnosis category of lymphoma

CC Kitanovski (ckitanovski@shield-legal.com)
2025-08-29 12:15:30

i thought it had some fancy words around it

James Scott (jamesscott@shield-legal.com)
2025-08-29 12:16:04

Maybe the other columns but I told cam this the other day to neoplasms is the medical category that skin cancer lymphoma falls under

CC Kitanovski (ckitanovski@shield-legal.com)
2025-08-29 12:19:02

see I knew there was a skin cancer mention in here, somewhere 😵‍💫

CC Kitanovski (ckitanovski@shield-legal.com)
2025-08-29 12:19:22

i'll go manually pull the FDA adverse event data and screenshot it to him.

CC Kitanovski (ckitanovski@shield-legal.com)
2025-08-29 13:06:31

@James Scott I went onto FAERS and pulled the data manually to answer Cam's question the long, manual, human way 💀 Like you said, all lymphoma-related adverse events fall under the reaction group "Neoplasms Benign, Malignant And Unspecified (Incl Cysts And Polyps)".

I totaled all adverse events where the word "lymphoma" appears in the reaction name, including Cutaneous T-Cell Lymphoma, Non-Hodgkin's Lymphoma, B-Cell Lymphoma, etc.

So far in 2025, we've got 10 different lymphoma adverse events totaling 61 cases out of 86,898 total Dupixent-related adverse events. Within the 2025 "Neoplasms Benign, Malignant And Unspecified" category (646 total cases), lymphoma events represent 9.4% of all neoplasm-related adverse events.

If we use all available FAERS data (2017-present), there are 32 different lymphoma adverse events totaling 365 cases out of 358,343 total Dupixent-related adverse events. Within the 2017-2025 "Neoplasms Benign, Malignant And Unspecified" category (2,838 total cases), lymphoma events represent 12.9% of all neoplasm-related adverse events.

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image.png
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FDA adverse events 2025.xlsx
FDA adverse events 2017-2025 total.xlsx
👍 James Scott
CC Kitanovski (ckitanovski@shield-legal.com)
2025-08-29 13:07:56

The good news is... I have validated your Medilens tool!! I got 646 cases under neoplasm for 2025!!

James Scott (jamesscott@shield-legal.com)
2025-08-29 13:21:33

Awesome !! Yes the data isn’t refreshed yet so ours would prob match when it does !

James Scott (jamesscott@shield-legal.com)
2025-08-29 13:21:45

You are a rockstar

CC Kitanovski (ckitanovski@shield-legal.com)
2025-08-29 13:21:49

I could swear it said 646 neoplasms

CC Kitanovski (ckitanovski@shield-legal.com)
2025-08-29 13:21:56

I am bad with words but good with numbers.

James Scott (jamesscott@shield-legal.com)
2025-08-29 13:23:22

i had 641

James Scott (jamesscott@shield-legal.com)
2025-08-29 13:23:25

so 5 cases lol

CC Kitanovski (ckitanovski@shield-legal.com)
2025-08-29 13:28:49

that is close enough!!!!!!! IT LIIIIIIIIIIIIIVES!!!!!!!!!!!!

James Scott (jamesscott@shield-legal.com)
2025-08-29 13:32:34

ahahha yes yes!! im excited as well, curious what did u go to shcool for

CC Kitanovski (ckitanovski@shield-legal.com)
2025-08-29 13:33:58

phd in chemistry, everyone's favorite subject. minored in math.

James Scott (jamesscott@shield-legal.com)
2025-08-29 13:35:10

mines was major in stats lol and phd !! i hated school lol

CC Kitanovski (ckitanovski@shield-legal.com)
2025-08-29 13:41:04

i figured if i was going to go, and i was going to be the only person in my family to ever go to college, and i wanted my three children to never be able to say the words "mom, I can't" to me... i should just go to all of the college.

CC Kitanovski (ckitanovski@shield-legal.com)
2025-08-29 13:41:21

therefore, i went to all of the college.